Abstract
A palladium mediated synthesis of a common synthon for the syntheses of antioxidant analogues of naturally occurring salvianolic acids is presented. The synthetic route may be used to obtain analogues with a balanced lipophilicity/hydrophilicity which may result in potentially interesting LDL antioxidants for the prevention of cardiovascular diseases.
Original language | English (US) |
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Pages (from-to) | 8654-8665 |
Number of pages | 12 |
Journal | Molecules |
Volume | 20 |
Issue number | 5 |
DOIs | |
State | Published - 2015 |
Externally published | Yes |
Keywords
- Antioxidant
- Benzofuran
- Palladium
ASJC Scopus subject areas
- Analytical Chemistry
- Chemistry (miscellaneous)
- Molecular Medicine
- Pharmaceutical Science
- Drug Discovery
- Physical and Theoretical Chemistry
- Organic Chemistry