Summating potential/action potential ratio in perilymph fistula

W. L. Meyerhoff, M. W. Yellin

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


A prospective study of electrocochleography in patients with clinically suspected perilymph fistula was undertaken to determine its predictive value in that disorder. One hundred forty-four patients suspected of having perilymph fistula had electrocochleography performed - 34 of these (39 ears) had exploratory tympanotomy. Of the 19 ears with normal preoperative summating potential/action potential (SP/AP) ratio, ten had perilymph fistula identified at the time of surgery. Of the 20 ears with abnormal SP/AP ratio, 16 had perilymph fistula confirmed at exploration, 18 had resolution of symptoms after oval window and round membrane grafting, and only one ear had postoperative persistence of the abnormal SP/AP ratio. This study suggests that an abnormal SP/AP ratio is not only predictive of endolymphatic hydrops, but also of perilymph fistula (both problems of inner ear fluid imbalance). This study also suggests that, while abnormal SP/AP ratio is fairly specific for inner ear fluid imbalance, it is not sensitive.

Original languageEnglish (US)
Pages (from-to)678-682
Number of pages5
JournalOtolaryngology - Head and Neck Surgery
Issue number6
StatePublished - 1990

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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