TY - JOUR
T1 - SPARSEMODr
T2 - Rapidly simulate spatially explicit and stochastic models of COVID-19 and other infectious diseases
AU - Mihaljevic, Joseph R.
AU - Borkovec, Seth
AU - Ratnavale, Saikanth
AU - Hocking, Toby D.
AU - Banister, Kelsey E.
AU - Eppinger, Joseph E.
AU - Hepp, Crystal
AU - Doerry, Eck
N1 - Publisher Copyright:
© 2022 The Author(s). Published by Oxford University Press.
PY - 2022
Y1 - 2022
N2 - Building realistically complex models of infectious disease transmission that are relevant for informing public health is conceptually challenging and requires knowledge of coding architecture that can implement key modeling conventions. For example, many of the models built to understand COVID-19 dynamics have included stochasticity, transmission dynamics that change throughout the epidemic due to changes in host behavior or public health interventions, and spatial structures that account for important spatio-temporal heterogeneities. Here we introduce an R package, SPARSEMODr, that allows users to simulate disease models that are stochastic and spatially explicit, including a model for COVID-19 that was useful in the early phases of the epidemic. SPARSEMOD stands for SPAtial Resolution-SEnsitive Models of Outbreak Dynamics, and our goal is to demonstrate particular conventions for rapidly simulating the dynamics of more complex, spatial models of infectious disease. In this report, we outline the features and workflows of our software package that allow for user-customized simulations. We believe the example models provided in our package will be useful in educational settings, as the coding conventions are adaptable, and will help new modelers to better understand important assumptions that were built into sophisticated COVID-19 models.
AB - Building realistically complex models of infectious disease transmission that are relevant for informing public health is conceptually challenging and requires knowledge of coding architecture that can implement key modeling conventions. For example, many of the models built to understand COVID-19 dynamics have included stochasticity, transmission dynamics that change throughout the epidemic due to changes in host behavior or public health interventions, and spatial structures that account for important spatio-temporal heterogeneities. Here we introduce an R package, SPARSEMODr, that allows users to simulate disease models that are stochastic and spatially explicit, including a model for COVID-19 that was useful in the early phases of the epidemic. SPARSEMOD stands for SPAtial Resolution-SEnsitive Models of Outbreak Dynamics, and our goal is to demonstrate particular conventions for rapidly simulating the dynamics of more complex, spatial models of infectious disease. In this report, we outline the features and workflows of our software package that allow for user-customized simulations. We believe the example models provided in our package will be useful in educational settings, as the coding conventions are adaptable, and will help new modelers to better understand important assumptions that were built into sophisticated COVID-19 models.
KW - C++
KW - R
KW - disease ecology
KW - epidemiological model
KW - host-pathogen interactions
KW - spatial disease models
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U2 - 10.1093/biomethods/bpac022
DO - 10.1093/biomethods/bpac022
M3 - Article
AN - SCOPUS:85153713813
SN - 2396-8923
VL - 7
JO - Biology Methods and Protocols
JF - Biology Methods and Protocols
IS - 1
M1 - bpac022
ER -