Silver nanocluster aptamers: In situ generation of intrinsically fluorescent recognition ligands for protein detection

Jaswinder Sharma; Hsin Chih Yeh; Hyojong Yoo; James H. Werner; Jennifer S. Martinez

doi:10.1039/c0cc03711g

Silver nanocluster aptamers: In situ generation of intrinsically fluorescent recognition ligands for protein detection

Jaswinder Sharma, Hsin Chih Yeh, Hyojong Yoo, James H. Werner, Jennifer S. Martinez

Research output: Contribution to journal › Article › peer-review

243 Scopus citations

Abstract

We have synthesized an intrinsically fluorescent recognition ligand that combines the high fluorescence quantum yield (>50%) of oligonucleotide templated AgNCs with the specificity and strong binding affinity of DNA aptamers for their target proteins, to develop a new strategy for detection of specific proteins.

Original language	English (US)
Pages (from-to)	2294-2296
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	8
DOIs	https://doi.org/10.1039/c0cc03711g
State	Published - Feb 7 2011
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c0cc03711g

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title = "Silver nanocluster aptamers: In situ generation of intrinsically fluorescent recognition ligands for protein detection",

abstract = "We have synthesized an intrinsically fluorescent recognition ligand that combines the high fluorescence quantum yield (>50\%) of oligonucleotide templated AgNCs with the specificity and strong binding affinity of DNA aptamers for their target proteins, to develop a new strategy for detection of specific proteins.",

author = "Jaswinder Sharma and Yeh, \{Hsin Chih\} and Hyojong Yoo and Werner, \{James H.\} and Martinez, \{Jennifer S.\}",

year = "2011",

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day = "7",

doi = "10.1039/c0cc03711g",

language = "English (US)",

volume = "47",

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journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T2 - In situ generation of intrinsically fluorescent recognition ligands for protein detection

AU - Sharma, Jaswinder

AU - Yeh, Hsin Chih

AU - Yoo, Hyojong

AU - Werner, James H.

AU - Martinez, Jennifer S.

PY - 2011/2/7

Y1 - 2011/2/7

N2 - We have synthesized an intrinsically fluorescent recognition ligand that combines the high fluorescence quantum yield (>50%) of oligonucleotide templated AgNCs with the specificity and strong binding affinity of DNA aptamers for their target proteins, to develop a new strategy for detection of specific proteins.

AB - We have synthesized an intrinsically fluorescent recognition ligand that combines the high fluorescence quantum yield (>50%) of oligonucleotide templated AgNCs with the specificity and strong binding affinity of DNA aptamers for their target proteins, to develop a new strategy for detection of specific proteins.

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UR - https://www.scopus.com/inward/citedby.url?scp=79751470678&partnerID=8YFLogxK

U2 - 10.1039/c0cc03711g

DO - 10.1039/c0cc03711g

M3 - Article

C2 - 21152540

AN - SCOPUS:79751470678

SN - 1359-7345

VL - 47

SP - 2294

EP - 2296

JO - Chemical Communications

JF - Chemical Communications

IS - 8

ER -

Silver nanocluster aptamers: In situ generation of intrinsically fluorescent recognition ligands for protein detection

Abstract

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