Silver nanocluster aptamers: In situ generation of intrinsically fluorescent recognition ligands for protein detection

Jaswinder Sharma, Hsin Chih Yeh, Hyojong Yoo, James H. Werner, Jennifer S. Martinez

Research output: Contribution to journalArticlepeer-review

225 Scopus citations

Abstract

We have synthesized an intrinsically fluorescent recognition ligand that combines the high fluorescence quantum yield (>50%) of oligonucleotide templated AgNCs with the specificity and strong binding affinity of DNA aptamers for their target proteins, to develop a new strategy for detection of specific proteins.

Original languageEnglish (US)
Pages (from-to)2294-2296
Number of pages3
JournalChemical Communications
Volume47
Issue number8
DOIs
StatePublished - Feb 7 2011
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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