Sex-biased infections scale to population impacts for an emerging wildlife disease

Macy J. Kailing, Joseph R. Hoyt, J. Paul White, Heather M. Kaarakka, Jennifer A. Redell, Ariel E. Leon, Tonie E. Rocke, John E. Depue, William H. Scullon, Katy L. Parise, Jeffrey T. Foster, A. Marm Kilpatrick, Kate E. Langwig

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Demographic factors are fundamental in shaping infectious disease dynamics. Aspects of populations that create structure, like age and sex, can affect patterns of transmission, infection intensity and population outcomes. However, studies rarely link these processes from individual to population-scale effects. Moreover, the mechanisms underlying demographic differences in disease are frequently unclear. Here, we explore sex-biased infections for a multi-host fungal disease of bats, white-nose syndrome, and link disease-associated mortality between sexes, the distortion of sex ratios and the potential mechanisms underlying sex differences in infection. We collected data on host traits, infection intensity and survival of five bat species at 42 sites across seven years. We found females were more infected than males for all five species. Females also had lower apparent survival over winter and accounted for a smaller proportion of populations over time. Notably, female-biased infections were evident by early hibernation and likely driven by sex-based differences in autumn mating behaviour. Male bats were more active during autumn which likely reduced replication of the cool-growing fungus. Higher disease impacts in female bats may have cascading effects on bat populations beyond the hibernation season by limiting recruitment and increasing the risk of Allee effects.

Original languageEnglish (US)
Article number20230040
JournalProceedings of the Royal Society B: Biological Sciences
Volume290
Issue number1995
DOIs
StatePublished - Mar 29 2023

Keywords

  • Allee effects
  • bats
  • emerging infectious disease
  • fungal disease
  • sex-biased infection
  • white-nose syndrome

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Immunology and Microbiology
  • General Environmental Science
  • General Agricultural and Biological Sciences

Fingerprint

Dive into the research topics of 'Sex-biased infections scale to population impacts for an emerging wildlife disease'. Together they form a unique fingerprint.

Cite this