Sentence memory affected by vasopressin analog (DDAVP) in cross-over experiment

Robert E. Till, Bill E. Beckwith

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


DDAVP has been shown to facilitate memory, especially retrieval, in humans. Healthy young male adult subjects received DDAVP (60 μg) in a cross-over design with a one-week interval between sessions. Results indicated that DDAVP improved immediate memory during the first but not the second testing session, particularly for low-verbal subjects. Treatment with DDAVP also facilitated delayed (one-week) recall in the opposite group, a cross-over interaction that suggests a retrieval locus for the DDAVP effect. Furthermore, since DDAVP improved immediate memory more for low-verbal subjects and delayed memory more for high-verbal subjects, it appears that individual difference factors will be important in understanding the effects of vasopressin on memory.

Original languageEnglish (US)
Pages (from-to)397-402
Number of pages6
Issue number3
StatePublished - 1985


  • Memory
  • Neuropeptide
  • Vasopressin

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Endocrinology
  • Cellular and Molecular Neuroscience


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