Sensitivity of avian intrapulmonary chemoreceptors to venous CO2 load

Steven C. Hempleman; Thomas P. Adamson; Ray E. Burger

doi:10.1016/0034-5687(86)90138-6

Sensitivity of avian intrapulmonary chemoreceptors to venous CO₂ load

Steven C. Hempleman, Thomas P. Adamson, Ray E. Burger

Biological Sciences

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

To investigate the response of individula intrapulmonary chemoreceptors (IPC) to venous CO₂ loads approximating moderate muscular exercise, we recorded vagal discharege from 33 IPC arising frmo the left lungs of 9 anesthetized, unidirectionally ventilated Pekin ducks. Each IPC was studied during control conditions (Pe_{CO₂ = 29.0 ± 0.8 Torr, PvCO₂} = 30.2 ± 0.6 Torr) and during venous CO₂ load (Pe_CO2 = 29.5 ± 0.7 Torr, Pv_CO2 = 51.5 ± 1.4 Torr). Venous loading was produced by increasing the percentate of CO₂ in the gas ventilating the right lung form 0 to 9-25% CO₂. The flow of 1% CO₂ through the left lung was adjusted to keep the left lung PE_CO₂ constant. During venous loading, discharge frequenceis indicated that the P_CO₂ at the receptive sites fell, on teh averaga, 1.6 ± 0.8 Torr.

Original language	English (US)
Pages (from-to)	53-60
Number of pages	8
Journal	Respiration Physiology
Volume	66
Issue number	1
DOIs	https://doi.org/10.1016/0034-5687(86)90138-6
State	Published - Oct 1986

Keywords

Duck
Exercise
Lung chemoreceptors
Mixed venous blood
Respiratory control
Ventilatory inhibition

ASJC Scopus subject areas

Physiology
Pulmonary and Respiratory Medicine

Access to Document

10.1016/0034-5687(86)90138-6

Cite this

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title = "Sensitivity of avian intrapulmonary chemoreceptors to venous CO2 load",

abstract = "To investigate the response of individula intrapulmonary chemoreceptors (IPC) to venous CO2 loads approximating moderate muscular exercise, we recorded vagal discharege from 33 IPC arising frmo the left lungs of 9 anesthetized, unidirectionally ventilated Pekin ducks. Each IPC was studied during control conditions (PeCO2 = 29.0 ± 0.8 Torr, PvCO2 = 30.2 ± 0.6 Torr) and during venous CO2 load (PeCO2 = 29.5 ± 0.7 Torr, PvCO2 = 51.5 ± 1.4 Torr). Venous loading was produced by increasing the percentate of CO2 in the gas ventilating the right lung form 0 to 9-25% CO2. The flow of 1% CO2 through the left lung was adjusted to keep the left lung PECO2 constant. During venous loading, discharge frequenceis indicated that the PCO2 at the receptive sites fell, on teh averaga, 1.6 ± 0.8 Torr.",

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author = "Hempleman, {Steven C.} and Adamson, {Thomas P.} and Burger, {Ray E.}",

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AU - Burger, Ray E.

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N2 - To investigate the response of individula intrapulmonary chemoreceptors (IPC) to venous CO2 loads approximating moderate muscular exercise, we recorded vagal discharege from 33 IPC arising frmo the left lungs of 9 anesthetized, unidirectionally ventilated Pekin ducks. Each IPC was studied during control conditions (PeCO2 = 29.0 ± 0.8 Torr, PvCO2 = 30.2 ± 0.6 Torr) and during venous CO2 load (PeCO2 = 29.5 ± 0.7 Torr, PvCO2 = 51.5 ± 1.4 Torr). Venous loading was produced by increasing the percentate of CO2 in the gas ventilating the right lung form 0 to 9-25% CO2. The flow of 1% CO2 through the left lung was adjusted to keep the left lung PECO2 constant. During venous loading, discharge frequenceis indicated that the PCO2 at the receptive sites fell, on teh averaga, 1.6 ± 0.8 Torr.

AB - To investigate the response of individula intrapulmonary chemoreceptors (IPC) to venous CO2 loads approximating moderate muscular exercise, we recorded vagal discharege from 33 IPC arising frmo the left lungs of 9 anesthetized, unidirectionally ventilated Pekin ducks. Each IPC was studied during control conditions (PeCO2 = 29.0 ± 0.8 Torr, PvCO2 = 30.2 ± 0.6 Torr) and during venous CO2 load (PeCO2 = 29.5 ± 0.7 Torr, PvCO2 = 51.5 ± 1.4 Torr). Venous loading was produced by increasing the percentate of CO2 in the gas ventilating the right lung form 0 to 9-25% CO2. The flow of 1% CO2 through the left lung was adjusted to keep the left lung PECO2 constant. During venous loading, discharge frequenceis indicated that the PCO2 at the receptive sites fell, on teh averaga, 1.6 ± 0.8 Torr.

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KW - Respiratory control

KW - Ventilatory inhibition

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