TY - CHAP
T1 - Procedures for the synthesis and capping of metal nanoparticles
AU - Gutiérrez-Wing, Claudia
AU - Velázquez-Salazar, J. Jesús
AU - José-Yacamán, Miguel
PY - 2012
Y1 - 2012
N2 - The increasing impact of metallic nanoparticles in life sciences has stimulated the development of new techniques and multiple improvements of the existing methods of manufacturing nanoparticles with tailored properties. Nanoparticles can be synthesized through a variety of physical and chemical methods. The choice of preparation procedure will depend on the physical and chemical characteristics required on the final product, such as size, dispersion, chemical miscibility, optical properties, among others. Here we review basic practical procedures used for the preparation of protected and unprotected metallic nanoparticles and describe a number of experimental procedures based on colloidal chemistry methods. These include gold nanoparticle synthesis by reduction with trisodium citrate, ascorbic acid, or sugars in aqueous phase; nanoparticle passivation with alkanethiols, cetyltrimethylammonium bromide, or bovin serum albumin. We also describe microwave-assisted synthesis, nanoparticle synthesis in ethylene glycol, template-assisted synthesis with dendrimers and briefly describe how to control nanoparticle shape (star-shaped and branched nanoparticles).
AB - The increasing impact of metallic nanoparticles in life sciences has stimulated the development of new techniques and multiple improvements of the existing methods of manufacturing nanoparticles with tailored properties. Nanoparticles can be synthesized through a variety of physical and chemical methods. The choice of preparation procedure will depend on the physical and chemical characteristics required on the final product, such as size, dispersion, chemical miscibility, optical properties, among others. Here we review basic practical procedures used for the preparation of protected and unprotected metallic nanoparticles and describe a number of experimental procedures based on colloidal chemistry methods. These include gold nanoparticle synthesis by reduction with trisodium citrate, ascorbic acid, or sugars in aqueous phase; nanoparticle passivation with alkanethiols, cetyltrimethylammonium bromide, or bovin serum albumin. We also describe microwave-assisted synthesis, nanoparticle synthesis in ethylene glycol, template-assisted synthesis with dendrimers and briefly describe how to control nanoparticle shape (star-shaped and branched nanoparticles).
KW - Colloidal particles
KW - Nanomaterials
KW - Nanoparticles
KW - Nanostructures synthesis
KW - Nanotechnology
KW - Passivated particles
UR - http://www.scopus.com/inward/record.url?scp=84864862360&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84864862360&partnerID=8YFLogxK
U2 - 10.1007/978-1-61779-953-2_1
DO - 10.1007/978-1-61779-953-2_1
M3 - Chapter
C2 - 22791420
AN - SCOPUS:84864862360
SN - 9781617799525
T3 - Methods in Molecular Biology
SP - 3
EP - 19
BT - Nanoparticles in Biology and Medicine
A2 - Soloviev, Mikhail
ER -