Precision epidemiology for infectious disease control

Jason T. Ladner; Nathan D. Grubaugh; Oliver G. Pybus; Kristian G. Andersen

doi:10.1038/s41591-019-0345-2

Precision epidemiology for infectious disease control

Jason T. Ladner, Nathan D. Grubaugh, Oliver G. Pybus, Kristian G. Andersen

Biological Sciences

Research output: Contribution to journal › Review article › peer-review

93 Scopus citations

Abstract

Advances in genomics and computing are transforming the capacity for the characterization of biological systems, and researchers are now poised for a precision-focused transformation in the way they prepare for, and respond to, infectious diseases. This includes the use of genome-based approaches to inform molecular diagnosis and individual-level treatment regimens. In addition, advances in the speed and granularity of pathogen genome generation have improved the capability to track and understand pathogen transmission, leading to potential improvements in the design and implementation of population-level public health interventions. In this Perspective, we outline several trends that are driving the development of precision epidemiology of infectious disease and their implications for scientists’ ability to respond to outbreaks.

Original language	English (US)
Pages (from-to)	206-211
Number of pages	6
Journal	Nature Medicine
Volume	25
Issue number	2
DOIs	https://doi.org/10.1038/s41591-019-0345-2
State	Published - Feb 1 2019

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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Precision epidemiology for infectious disease control

Abstract

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