Precision epidemiology for infectious disease control

Jason T. Ladner, Nathan D. Grubaugh, Oliver G. Pybus, Kristian G. Andersen

Research output: Contribution to journalReview articlepeer-review

55 Scopus citations

Abstract

Advances in genomics and computing are transforming the capacity for the characterization of biological systems, and researchers are now poised for a precision-focused transformation in the way they prepare for, and respond to, infectious diseases. This includes the use of genome-based approaches to inform molecular diagnosis and individual-level treatment regimens. In addition, advances in the speed and granularity of pathogen genome generation have improved the capability to track and understand pathogen transmission, leading to potential improvements in the design and implementation of population-level public health interventions. In this Perspective, we outline several trends that are driving the development of precision epidemiology of infectious disease and their implications for scientists’ ability to respond to outbreaks.

Original languageEnglish (US)
Pages (from-to)206-211
Number of pages6
JournalNature Medicine
Volume25
Issue number2
DOIs
StatePublished - Feb 1 2019

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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