Polythiophenes in biological applications

Prakash Sista, Koushik Ghosh, Jennifer S. Martinez, Reginaldo C. Rocha

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations

Abstract

Polythiophene and its derivatives have shown tremendous potential for interfacing electrically conducting polymers with biological applications. These semiconducting organic polymers are relatively soft, conduct electrons and ions, have low cytotoxicity, and can undergo facile chemical modifications. In addition, the reduction in electrical impedance of electrodes coated with polythiophenes may prove to be invaluable for a stable and permanent connection between devices and biological tissues. This review article focuses on the synthesis and some key applications of polythiophenes in multidisciplinary areas at the interface with biology. These polymers have shown tremendous potential in biological applications such as diagnostics, therapy, drug delivery, imaging, implant devices and artificial organs.

Original languageEnglish (US)
Pages (from-to)250-272
Number of pages23
JournalJournal of Nanoscience and Nanotechnology
Volume14
Issue number1
DOIs
StatePublished - Jan 2014
Externally publishedYes

Keywords

  • Applications
  • Artificial organs
  • Diagnostics
  • Drug delivery
  • Imaging
  • Implant devices
  • Polythiophenes
  • Therapy

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)
  • Condensed Matter Physics

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