Phylogeography of Francisella tularensis ssp. holarctica in France

A. J. Vogler; D. N. Birdsell; J. Lee; J. Vaissaire; C. L. Doujet; M. Lapalus; D. M. Wagner; P. Keim

doi:10.1111/j.1472-765X.2010.02977.x

Phylogeography of Francisella tularensis ssp. holarctica in France

A. J. Vogler, D. N. Birdsell, J. Lee, J. Vaissaire, C. L. Doujet, M. Lapalus, D. M. Wagner, P. Keim

Biological Sciences

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Aim: To investigate the phylogeography of French Francisella tularensis ssp. holarctica isolates.Methods and Results: Canonical SNPs and MLVA were used to genotype 103 French F. tularensis ssp. holarctica isolates. We confirmed the presence of one subclade, the central and western European group (B.Br.FTNF002-00), and identified four major MLVA genotypes with no obvious geographical differentiation.Conclusions: The lack of geographical resolution among MLVA genotypes suggests rapid dispersal, convergent evolution or a combination of the two.Significance and Impact of the Study: This study expands knowledge of the phylogeography of one of the two dominant European F. tularensis ssp. holarctica subclades and illustrates the need for additional SNP discovery within this subclade.

Original language	English (US)
Pages (from-to)	177-180
Number of pages	4
Journal	Letters in Applied Microbiology
Volume	52
Issue number	2
DOIs	https://doi.org/10.1111/j.1472-765X.2010.02977.x
State	Published - Feb 2011

Keywords

France
Francisella tularensis
MLVA
SNP
VNTR
holarctica

ASJC Scopus subject areas

Applied Microbiology and Biotechnology

Access to Document

10.1111/j.1472-765X.2010.02977.x

Cite this

@article{d0da952dbf654be79230a6a76dd7b5dc,

title = "Phylogeography of Francisella tularensis ssp. holarctica in France",

abstract = "Aim: To investigate the phylogeography of French Francisella tularensis ssp. holarctica isolates.Methods and Results: Canonical SNPs and MLVA were used to genotype 103 French F. tularensis ssp. holarctica isolates. We confirmed the presence of one subclade, the central and western European group (B.Br.FTNF002-00), and identified four major MLVA genotypes with no obvious geographical differentiation.Conclusions: The lack of geographical resolution among MLVA genotypes suggests rapid dispersal, convergent evolution or a combination of the two.Significance and Impact of the Study: This study expands knowledge of the phylogeography of one of the two dominant European F. tularensis ssp. holarctica subclades and illustrates the need for additional SNP discovery within this subclade.",

keywords = "France, Francisella tularensis, MLVA, SNP, VNTR, holarctica",

author = "Vogler, \{A. J.\} and Birdsell, \{D. N.\} and J. Lee and J. Vaissaire and Doujet, \{C. L.\} and M. Lapalus and Wagner, \{D. M.\} and P. Keim",

year = "2011",

month = feb,

doi = "10.1111/j.1472-765X.2010.02977.x",

language = "English (US)",

volume = "52",

pages = "177--180",

journal = "Letters in Applied Microbiology",

issn = "0266-8254",

publisher = "Oxford University Press",

number = "2",

}

TY - JOUR

T1 - Phylogeography of Francisella tularensis ssp. holarctica in France

AU - Vogler, A. J.

AU - Birdsell, D. N.

AU - Lee, J.

AU - Vaissaire, J.

AU - Doujet, C. L.

AU - Lapalus, M.

AU - Wagner, D. M.

AU - Keim, P.

PY - 2011/2

Y1 - 2011/2

N2 - Aim: To investigate the phylogeography of French Francisella tularensis ssp. holarctica isolates.Methods and Results: Canonical SNPs and MLVA were used to genotype 103 French F. tularensis ssp. holarctica isolates. We confirmed the presence of one subclade, the central and western European group (B.Br.FTNF002-00), and identified four major MLVA genotypes with no obvious geographical differentiation.Conclusions: The lack of geographical resolution among MLVA genotypes suggests rapid dispersal, convergent evolution or a combination of the two.Significance and Impact of the Study: This study expands knowledge of the phylogeography of one of the two dominant European F. tularensis ssp. holarctica subclades and illustrates the need for additional SNP discovery within this subclade.

AB - Aim: To investigate the phylogeography of French Francisella tularensis ssp. holarctica isolates.Methods and Results: Canonical SNPs and MLVA were used to genotype 103 French F. tularensis ssp. holarctica isolates. We confirmed the presence of one subclade, the central and western European group (B.Br.FTNF002-00), and identified four major MLVA genotypes with no obvious geographical differentiation.Conclusions: The lack of geographical resolution among MLVA genotypes suggests rapid dispersal, convergent evolution or a combination of the two.Significance and Impact of the Study: This study expands knowledge of the phylogeography of one of the two dominant European F. tularensis ssp. holarctica subclades and illustrates the need for additional SNP discovery within this subclade.

KW - France

KW - Francisella tularensis

KW - MLVA

KW - SNP

KW - VNTR

KW - holarctica

UR - https://www.scopus.com/pages/publications/78650972034

UR - https://www.scopus.com/inward/citedby.url?scp=78650972034&partnerID=8YFLogxK

U2 - 10.1111/j.1472-765X.2010.02977.x

DO - 10.1111/j.1472-765X.2010.02977.x

M3 - Article

C2 - 21214606

AN - SCOPUS:78650972034

SN - 0266-8254

VL - 52

SP - 177

EP - 180

JO - Letters in Applied Microbiology

JF - Letters in Applied Microbiology

IS - 2

ER -

Phylogeography of Francisella tularensis ssp. holarctica in France

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this