Phylogeography of Francisella tularensis ssp. holarctica in France

A. J. Vogler, D. N. Birdsell, J. Lee, J. Vaissaire, C. L. Doujet, M. Lapalus, D. M. Wagner, P. Keim

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Aim: To investigate the phylogeography of French Francisella tularensis ssp. holarctica isolates.Methods and Results: Canonical SNPs and MLVA were used to genotype 103 French F. tularensis ssp. holarctica isolates. We confirmed the presence of one subclade, the central and western European group (B.Br.FTNF002-00), and identified four major MLVA genotypes with no obvious geographical differentiation.Conclusions: The lack of geographical resolution among MLVA genotypes suggests rapid dispersal, convergent evolution or a combination of the two.Significance and Impact of the Study: This study expands knowledge of the phylogeography of one of the two dominant European F. tularensis ssp. holarctica subclades and illustrates the need for additional SNP discovery within this subclade.

Original languageEnglish (US)
Pages (from-to)177-180
Number of pages4
JournalLetters in Applied Microbiology
Issue number2
StatePublished - Feb 2011


  • France
  • Francisella tularensis
  • MLVA
  • SNP
  • VNTR
  • holarctica

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology


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