@article{9047ef8cbb884351b596a5f690c2f759,
title = "Phenylpropanoid glycosides of Mimulus guttatus (yellow monkeyflower)",
abstract = "Yellow monkeyflower [Mimulus guttatus DC., (Phyrmaceae)] has long been a model plant species for studies in genetics, evolution, and ecology, including plant-animal interactions. Nonetheless, exceedingly little is known about its secondary chemistry. We have discovered that the foliage of yellow monkeyflower contains a diverse suite of phenylpropanoid glycosides (PPGs); a class of compounds with many known biological activities. Using 1H and 13C NMR and UV and MS chromatography techniques, we positively identified five PPGs from the leaves of yellow monkeyflower. Four of these compounds occur in other species and one is previously undescribed. We also present UV and high-resolution tandem MS data that putatively identify 11 additional foliar compounds as PPGs. This initial discovery and elucidation of yellow monkeyflower's secondary chemistry will be important for continued study of the genetics and ecology of this model species.",
keywords = "Calceolarioside, Conandroside, Mimuloside, Mimulus guttatus, Phenylpropanoid glycosides, Verbascoside",
author = "Ken Keefover-Ring and Holeski, {Liza M.} and Bowers, {M. Deane} and Clauss, {Allen D.} and Lindroth, {Richard L.}",
note = "Funding Information: Special thanks to Prof. S{\o}ren Jensen for helpful comments on various drafts of this work and confirmation of mimuloside as a new PPG. In addition, the comments from several anonymous reviewers greatly strengthened this paper. We also thank Marcus Carlsson for advice on compound isolation, purification, NMR interpretation, and use of equipment. Maria Ahnlund shared her mass spectrometry expertise and conducted much of the MS/MS work. Greg Barrett-Wilt provided help with MS/MS interpretation. This study made use of the National Magnetic Resonance Facility at Madison (NMRFAM), which is supported by NIH grants P41RR02301 (BRTP/NCRR) and P41GM66326 (NIGMS). We also thank Mark Anderson, Rita Hannah, and Jameson Bothe at NMRFAM for assistance with running NMR samples. The Mimulus seed library (Duke University) and D. Lowry generously provided some of the seeds used in this study. Funding for this research was provided by National Science Foundation grants DEB-0425908 and DEB-0841609 to RLL. Publisher Copyright: {\textcopyright} 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.",
year = "2014",
month = dec,
doi = "10.1016/j.phytol.2014.08.016",
language = "English (US)",
volume = "10",
pages = "132--139",
journal = "Phytochemistry Letters",
issn = "1874-3900",
publisher = "Elsevier BV",
}