TY - JOUR
T1 - Marine amphiphilic siderophores
T2 - Marinobactin structure, uptake, and microbial partitioning
AU - Martinez, Jennifer S.
AU - Butler, Alison
N1 - Funding Information:
Support from NIH GM38130 (AB) and NSF CHE-0221978 (Center for Environmental BioInorganic Chemistry, a NSF Environmental Molecular Science Institute) is gratefully acknowledged. We thank California Sea Grant for a graduate student traineeship for JSM.
PY - 2007/11
Y1 - 2007/11
N2 - Marinobactins A-E are a suite of amphiphilic siderophores which have a common peptidic head group that coordinates Fe(III), and a fatty acid which varies in length and saturation. As a result of the amphiphilic properties of these siderophores it is difficult to study siderophore-mediated uptake of iron, because the amphiphilic siderophores partition indiscriminately in microbial and other membranes. An alternative method to distinguish amphiphilic siderophore partitioning versus siderophore-mediated active uptake for Fe(III)-marinobactin E has been developed. In addition, a new member of the marinobactin family of siderophores is also reported, marinobactin F, which has a C18 fatty acid with one double bond and which is substantially more hydrophobic that marinobactins A-E.
AB - Marinobactins A-E are a suite of amphiphilic siderophores which have a common peptidic head group that coordinates Fe(III), and a fatty acid which varies in length and saturation. As a result of the amphiphilic properties of these siderophores it is difficult to study siderophore-mediated uptake of iron, because the amphiphilic siderophores partition indiscriminately in microbial and other membranes. An alternative method to distinguish amphiphilic siderophore partitioning versus siderophore-mediated active uptake for Fe(III)-marinobactin E has been developed. In addition, a new member of the marinobactin family of siderophores is also reported, marinobactin F, which has a C18 fatty acid with one double bond and which is substantially more hydrophobic that marinobactins A-E.
KW - Amphiphilic siderophore
KW - Iron
KW - Lipidic peptide
KW - Marine bacteria
KW - Marinobactins
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U2 - 10.1016/j.jinorgbio.2007.07.007
DO - 10.1016/j.jinorgbio.2007.07.007
M3 - Article
C2 - 17868890
AN - SCOPUS:35348928750
SN - 0162-0134
VL - 101
SP - 1692
EP - 1698
JO - Journal of Inorganic Biochemistry
JF - Journal of Inorganic Biochemistry
IS - 11-12
ER -