Marine amphiphilic siderophores: Marinobactin structure, uptake, and microbial partitioning

Jennifer S. Martinez, Alison Butler

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

Marinobactins A-E are a suite of amphiphilic siderophores which have a common peptidic head group that coordinates Fe(III), and a fatty acid which varies in length and saturation. As a result of the amphiphilic properties of these siderophores it is difficult to study siderophore-mediated uptake of iron, because the amphiphilic siderophores partition indiscriminately in microbial and other membranes. An alternative method to distinguish amphiphilic siderophore partitioning versus siderophore-mediated active uptake for Fe(III)-marinobactin E has been developed. In addition, a new member of the marinobactin family of siderophores is also reported, marinobactin F, which has a C18 fatty acid with one double bond and which is substantially more hydrophobic that marinobactins A-E.

Original languageEnglish (US)
Pages (from-to)1692-1698
Number of pages7
JournalJournal of Inorganic Biochemistry
Volume101
Issue number11-12
DOIs
StatePublished - Nov 2007
Externally publishedYes

Keywords

  • Amphiphilic siderophore
  • Iron
  • Lipidic peptide
  • Marine bacteria
  • Marinobactins

ASJC Scopus subject areas

  • Biochemistry
  • Inorganic Chemistry

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