Low molecular weight immunosuppressors secreted by adult Nematospiroides dubius

Fernando G. Monroy; Colin Dobson; John H. Adams

doi:10.1016/0020-7519(89)90030-1

Low molecular weight immunosuppressors secreted by adult Nematospiroides dubius

Fernando G. Monroy, Colin Dobson, John H. Adams

Biological Sciences

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Low molecular weight immunosuppressors secreted by adult Nematospiroides dubius. International Journal for Parasitology 19: 125-127. Adult Nematospiroides dubius excretory-secretory products (ES) were collected from worms cultured in vitro, separated by sodium dodecyi sulphatepolyacrylamide gel electrophoresis (SDS-PAGE) into four fractions (FI-IV), electroeluted and assessed for their ability to inhibit the proliferation of mouse lymphocytes stimulated by mitogens in vitro. The proliferation of milogen- and ES-stimulated mouse spleen lymphocytes from normal and infected mice was inhibited by low mol. wt ES F-IV (<26,000).

Original language	English (US)
Pages (from-to)	125-127
Number of pages	3
Journal	International Journal for Parasitology
Volume	19
Issue number	1
DOIs	https://doi.org/10.1016/0020-7519(89)90030-1
State	Published - Feb 1989

Keywords

Nemalospiroides dubius
excretory-secretory antigens
immunosuppression
mitogens

ASJC Scopus subject areas

Parasitology
Infectious Diseases

Access to Document

10.1016/0020-7519(89)90030-1

Cite this

@article{729527d8fea24ad99f16d3a72f3865b7,

title = "Low molecular weight immunosuppressors secreted by adult Nematospiroides dubius",

abstract = "Low molecular weight immunosuppressors secreted by adult Nematospiroides dubius. International Journal for Parasitology 19: 125-127. Adult Nematospiroides dubius excretory-secretory products (ES) were collected from worms cultured in vitro, separated by sodium dodecyi sulphatepolyacrylamide gel electrophoresis (SDS-PAGE) into four fractions (FI-IV), electroeluted and assessed for their ability to inhibit the proliferation of mouse lymphocytes stimulated by mitogens in vitro. The proliferation of milogen- and ES-stimulated mouse spleen lymphocytes from normal and infected mice was inhibited by low mol. wt ES F-IV (<26,000).",

keywords = "Nemalospiroides dubius, excretory-secretory antigens, immunosuppression, mitogens",

author = "Monroy, {Fernando G.} and Colin Dobson and Adams, {John H.}",

year = "1989",

month = feb,

doi = "10.1016/0020-7519(89)90030-1",

language = "English (US)",

volume = "19",

pages = "125--127",

journal = "International Journal for Parasitology",

issn = "0020-7519",

publisher = "Elsevier Limited",

number = "1",

}

TY - JOUR

T1 - Low molecular weight immunosuppressors secreted by adult Nematospiroides dubius

AU - Monroy, Fernando G.

AU - Dobson, Colin

AU - Adams, John H.

PY - 1989/2

Y1 - 1989/2

N2 - Low molecular weight immunosuppressors secreted by adult Nematospiroides dubius. International Journal for Parasitology 19: 125-127. Adult Nematospiroides dubius excretory-secretory products (ES) were collected from worms cultured in vitro, separated by sodium dodecyi sulphatepolyacrylamide gel electrophoresis (SDS-PAGE) into four fractions (FI-IV), electroeluted and assessed for their ability to inhibit the proliferation of mouse lymphocytes stimulated by mitogens in vitro. The proliferation of milogen- and ES-stimulated mouse spleen lymphocytes from normal and infected mice was inhibited by low mol. wt ES F-IV (<26,000).

AB - Low molecular weight immunosuppressors secreted by adult Nematospiroides dubius. International Journal for Parasitology 19: 125-127. Adult Nematospiroides dubius excretory-secretory products (ES) were collected from worms cultured in vitro, separated by sodium dodecyi sulphatepolyacrylamide gel electrophoresis (SDS-PAGE) into four fractions (FI-IV), electroeluted and assessed for their ability to inhibit the proliferation of mouse lymphocytes stimulated by mitogens in vitro. The proliferation of milogen- and ES-stimulated mouse spleen lymphocytes from normal and infected mice was inhibited by low mol. wt ES F-IV (<26,000).

KW - Nemalospiroides dubius

KW - excretory-secretory antigens

KW - immunosuppression

KW - mitogens

UR - http://www.scopus.com/inward/record.url?scp=0024619190&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024619190&partnerID=8YFLogxK

U2 - 10.1016/0020-7519(89)90030-1

DO - 10.1016/0020-7519(89)90030-1

M3 - Article

C2 - 2707958

AN - SCOPUS:0024619190

SN - 0020-7519

VL - 19

SP - 125

EP - 127

JO - International Journal for Parasitology

JF - International Journal for Parasitology

IS - 1

ER -

Low molecular weight immunosuppressors secreted by adult Nematospiroides dubius

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this