Lithographically defined 3D nanoporous nonenzymatic glucose sensors

Xiaoyin Xiao, Gabriel A. Montaño, Thayne L. Edwards, Cody M. Washburn, Susan M. Brozik, David R. Wheeler, D. Bruce Burckel, Ronen Polsky

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Nonenzymatic glucose oxidation is demonstrated on highly faceted palladium nanowflower-modified porous carbon electrodes fabricated by interference lithography. Varying electrodeposition parameters were used to control the final shape and morphology of the deposited nanoparticles on the 3D porous carbon which showed a 12 times increase in the electrochemically active surface area over analogous planar electrodes. Extremely fast amperometric glucose responses (achieving 95% of the steady state limiting current in less than 5. s) with a linear range from 1 to 10. mM and a detection limit of 10μM were demonstrated. The unusual surface properties of the pyrolyzed photoresist films produced strongly adhered palladium crystal structures that were stable for hundreds of cycles towards glucose oxidation without noticeable current decay.

Original languageEnglish (US)
Pages (from-to)3641-3646
Number of pages6
JournalBiosensors and Bioelectronics
Issue number8
StatePublished - Apr 15 2011
Externally publishedYes


  • Glucose
  • Interference lithography
  • Palladium nanoflowers
  • Porous carbon

ASJC Scopus subject areas

  • Biotechnology
  • Biophysics
  • Biomedical Engineering
  • Electrochemistry


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