Lipid a remodeling is a pathoadaptive mechanism that impacts lipopolysaccharide recognition and intracellular survival of Burkholderia pseudomallei

Agriculture & Biology

• Burkholderia pseudomallei 100%
• lipid A 92%
• caspase-11 74%
• lipopolysaccharides 66%
• matrix-assisted laser desorption-ionization mass spectrometry 40%
• lipids 37%
• sepsis (infection) 33%
• pyroptosis 22%
• melioidosis 17%
• surface plasmon resonance 16%
• mutants 13%
• tumor necrosis factor-alpha 12%
• immune system 10%
• cell death 10%
• cytosol 10%
• macrophages 10%
• binding proteins 10%
• cytotoxicity 9%
• complement 9%
• virulence 9%
• cells 7%
• gene expression 7%
• pathogens 6%
• bacteria 6%
• infection 6%

Medicine & Life Sciences

• Burkholderia pseudomallei 99%
• Lipid A 93%
• Lipopolysaccharides 59%
• Lipids 45%
• Caspases 35%
• Mass Spectrometry 31%
• Lasers 28%
• Sepsis 18%
• lipopolysaccharide-binding protein 17%
• Melioidosis 16%
• Pyroptosis 15%
• Surface Plasmon Resonance 14%
• Virulence Factors 12%
• Growth 11%
• Cytosol 11%
• Immune System 9%
• Cell Death 8%
• Temperature 8%
• Tumor Necrosis Factor-alpha 8%
• Macrophages 8%
• Bacteria 7%
• Gene Expression 6%
• Mortality 5%
• Infections 5%