TY - JOUR
T1 - Life-Space Mobility and Cognitive Decline Among Mexican Americans Aged 75 Years and Older
AU - Silberschmidt, Seraina
AU - Kumar, Amit
AU - Raji, Mukaila M.
AU - Markides, Kyriakos
AU - Ottenbacher, Kenneth J.
AU - Al Snih, Soham
N1 - Funding Information:
This study was supported in part by grants R01-AG017638, R01-AG010939, R03 AG04640902, R01MD010355, and the UTMB Claude Pepper Center (P30-AG024832) from the National Institute of Aging. Seraina Silberschmidt was a Visiting Scholar in the Sealy Center on Aging. The content is solely the responsibility of the author(s) and does not represent the official views of this Institute or the National Institutes of Health. The authors acknowledge the assistance of Sarah Toombs Smith, PhD, ELS, in manuscript preparation. Conflicts of Interest: None. Funding: This study was supported in part by grants R01-AG017638, R01-AG010939, R03 AG04640902, R01MD010355, and the UTMB Claude Pepper Center (P30-AG024832) from the National Institute of Aging. Author Contributions: Data access: Kenneth J Ottenbacher, Kyriakos S Markides, and Soham Al Snih had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Seraina Silberschmidt and Soham Al Snih. Acquisition, analysis, or interpretation of data: Seraina Silberschmidt and Soham Al Snih. Drafting of manuscript: Seraina Silberschmidt, Amit Kumar, and Soham Al Snih. Critical review: Seraina Silberschmidt, Amit Kumar, Kyriakos S Markides, Soham Al Snih, Mukaila A Raji, and Kenneth J Ottenbacher. Statistical analysis: Seraina Silberschmidt and Soham Al Snih. Administrative, technical, or material support: Ottenbacher, Al Snih, and Markides. Funding: Ottenbacher and Markides. Study supervision: Al Snih. Sponsor's Role: None.
Publisher Copyright:
© 2017, The American Geriatrics Society
PY - 2017/7
Y1 - 2017/7
N2 - Objectives: To examine the association between life-space mobility and cognitive decline over a five-year period among older Mexican Americans. Design: Longitudinal study. Setting: Hispanic Established Population for the Epidemiologic Study of the Elderly survey conducted in the southwestern of United States (Texas, Colorado, Arizona, New Mexico, and California). Participants: Four hundred thirty-two Mexican Americans aged 75 and older with normal or high cognitive function at baseline. Measurements: Socio-demographic factors, living arrangement, type of household, social support, financial strain, self-reported medical conditions, Mini-Mental State Examination (MMSE), depressive symptoms, activities of daily living (ADLs), and Short Physical Performance Battery. Life-space assessment (LSA) during the past 4 weeks was assessed during in-home interview. Scores ranged from 0 (daily restriction to the bedroom) to 120 (daily trips outside of their own town without assistance) and categorized as 0 to 20, 21 to 40, 41 to 60, 61 to 80, and 81 to 120. Because of the small sample size in the category of 81 to 120, the two highest categories were combined into a single group. Results: The mean LSA score and MMSE score of participants at baseline was 44.6 (Standard Deviation [SD], 20.7) and 25.7 (SD, 3.2), respectively. Mixed Model analyses showed that participants in the highest life-space category (≥61) experienced slower rates of cognitive decline over time compared to participants in the lowest category (0 to 20) (β = 1.03, Standard Error [SE] = 0.29, P = 0.0004), after adjusting for all covariates. Conclusion: Greater life-space mobility at baseline was predictor of slower rates of cognitive decline over 5 years in older Mexican Americans.
AB - Objectives: To examine the association between life-space mobility and cognitive decline over a five-year period among older Mexican Americans. Design: Longitudinal study. Setting: Hispanic Established Population for the Epidemiologic Study of the Elderly survey conducted in the southwestern of United States (Texas, Colorado, Arizona, New Mexico, and California). Participants: Four hundred thirty-two Mexican Americans aged 75 and older with normal or high cognitive function at baseline. Measurements: Socio-demographic factors, living arrangement, type of household, social support, financial strain, self-reported medical conditions, Mini-Mental State Examination (MMSE), depressive symptoms, activities of daily living (ADLs), and Short Physical Performance Battery. Life-space assessment (LSA) during the past 4 weeks was assessed during in-home interview. Scores ranged from 0 (daily restriction to the bedroom) to 120 (daily trips outside of their own town without assistance) and categorized as 0 to 20, 21 to 40, 41 to 60, 61 to 80, and 81 to 120. Because of the small sample size in the category of 81 to 120, the two highest categories were combined into a single group. Results: The mean LSA score and MMSE score of participants at baseline was 44.6 (Standard Deviation [SD], 20.7) and 25.7 (SD, 3.2), respectively. Mixed Model analyses showed that participants in the highest life-space category (≥61) experienced slower rates of cognitive decline over time compared to participants in the lowest category (0 to 20) (β = 1.03, Standard Error [SE] = 0.29, P = 0.0004), after adjusting for all covariates. Conclusion: Greater life-space mobility at baseline was predictor of slower rates of cognitive decline over 5 years in older Mexican Americans.
KW - Mexican Americans
KW - cognition
KW - life-space
KW - mobility
KW - older adults
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U2 - 10.1111/jgs.14829
DO - 10.1111/jgs.14829
M3 - Article
C2 - 28276089
AN - SCOPUS:85014802260
SN - 0002-8614
VL - 65
SP - 1514
EP - 1520
JO - Journal of the American Geriatrics Society
JF - Journal of the American Geriatrics Society
IS - 7
ER -