TY - GEN
T1 - Lattice Light-Sheet with Two-Color Incoherent Holography
AU - Potcoava, Mariana
AU - Mann, Christopher
AU - Art, John
AU - Alford, Simon
N1 - Funding Information:
We demonstrated IHLLS-2L imaging in two colors, 488 nm and 561 nm. Simultaneous excitation and faster detection of multiple fluorescent molecules using multiple wavelengths, will enable high temporal resolution of the spatial relationships between cellular structures. It is the relative dynamical changes between proteins, and lipid compartments that drive physiological signaling and cellular pathologies. Thus, for example the temporal resolution and quantification of interacting proteins during loss of cellular compartments is critical to our understanding of neurodegeneration. The authors acknowledge financial support from the NIH RO1 NS111749, and NIH R21 DC017292, and NSF (456789).
Publisher Copyright:
© 2022 The Author(s).
PY - 2022
Y1 - 2022
N2 - We introduce two-color incoherent holography lattice light-sheet system with a detection module that scans an extended FOV of 208x208 μm2, to provide quantitative monitoring of cellular dynamics in live tissue.
AB - We introduce two-color incoherent holography lattice light-sheet system with a detection module that scans an extended FOV of 208x208 μm2, to provide quantitative monitoring of cellular dynamics in live tissue.
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UR - http://www.scopus.com/inward/citedby.url?scp=85136411146&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85136411146
T3 - Optics InfoBase Conference Papers
BT - Optics and the Brain, BRAIN 2022
PB - Optica Publishing Group (formerly OSA)
T2 - Optics and the Brain, BRAIN 2022
Y2 - 24 April 2022 through 27 April 2022
ER -