Inspiratory loading and limb locomotor and respiratory muscle deoxygenation during cycling exercise

Louise A. Turner; Sandra Tecklenburg-Lund; Robert F. Chapman; Joel M. Stager; Joseph W. Duke; Timothy D. Mickleborough

doi:10.1016/j.resp.2012.11.018

Inspiratory loading and limb locomotor and respiratory muscle deoxygenation during cycling exercise

Louise A. Turner, Sandra Tecklenburg-Lund, Robert F. Chapman, Joel M. Stager, Joseph W. Duke, Timothy D. Mickleborough

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

The aim of this study was to determine the effect of inspiratory loading on limb locomotor (LM) and respiratory muscle (RM) deoxygenation ([deoxy (Hb+Mb)]) using NIRS during constant-power cycling exercise. Sixteen, male cyclists completed three, 6-min trials. The intensity of the first 3-min of each trial was equivalent to ∼80% V̇O2max (EX_80%); during the final 3-min, subjects received an intervention consisting of either moderate inspiratory loading (Load_mod), heavy inspiratory loading (Load_heavy), or maximal exercise (Load_EX). Load_heavy significantly increased LM [deoxy(Hb+Mb)] from 12.2±9.0μm during EX_80% to 15.3±11.7μm, and RM [deoxy(Hb+Mb)] from 5.9±3.6μm to 9.5±6.6μm. LM and RM [deoxy(Hb+Mb)] were significantly increased from EX_80% to Load_EX; 12.8±9.1μm to 16.4±10.3μm and 5.9±2.9μm to 11.0±6.4μm, respectively. These data suggest an increase in respiratory muscle load increases muscle deoxy(Hb+Mb) and thus may indicate a reduction in oxygen delivery and/or increased oxygen extraction by the active muscles.

Original language	English (US)
Pages (from-to)	506-514
Number of pages	9
Journal	Respiratory Physiology and Neurobiology
Volume	185
Issue number	3
DOIs	https://doi.org/10.1016/j.resp.2012.11.018
State	Published - Feb 1 2013
Externally published	Yes

Keywords

Muscle oxygenation
Near-infrared spectroscopy
Resistive breathing

ASJC Scopus subject areas

General Neuroscience
Physiology
Pulmonary and Respiratory Medicine

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title = "Inspiratory loading and limb locomotor and respiratory muscle deoxygenation during cycling exercise",

abstract = "The aim of this study was to determine the effect of inspiratory loading on limb locomotor (LM) and respiratory muscle (RM) deoxygenation ([deoxy (Hb+Mb)]) using NIRS during constant-power cycling exercise. Sixteen, male cyclists completed three, 6-min trials. The intensity of the first 3-min of each trial was equivalent to ∼80\% {\.V}O2max (EX80\%); during the final 3-min, subjects received an intervention consisting of either moderate inspiratory loading (Loadmod), heavy inspiratory loading (Loadheavy), or maximal exercise (LoadEX). Loadheavy significantly increased LM [deoxy(Hb+Mb)] from 12.2±9.0μm during EX80\% to 15.3±11.7μm, and RM [deoxy(Hb+Mb)] from 5.9±3.6μm to 9.5±6.6μm. LM and RM [deoxy(Hb+Mb)] were significantly increased from EX80\% to LoadEX; 12.8±9.1μm to 16.4±10.3μm and 5.9±2.9μm to 11.0±6.4μm, respectively. These data suggest an increase in respiratory muscle load increases muscle deoxy(Hb+Mb) and thus may indicate a reduction in oxygen delivery and/or increased oxygen extraction by the active muscles.",

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author = "Turner, \{Louise A.\} and Sandra Tecklenburg-Lund and Chapman, \{Robert F.\} and Stager, \{Joel M.\} and Duke, \{Joseph W.\} and Mickleborough, \{Timothy D.\}",

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AU - Duke, Joseph W.

AU - Mickleborough, Timothy D.

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N2 - The aim of this study was to determine the effect of inspiratory loading on limb locomotor (LM) and respiratory muscle (RM) deoxygenation ([deoxy (Hb+Mb)]) using NIRS during constant-power cycling exercise. Sixteen, male cyclists completed three, 6-min trials. The intensity of the first 3-min of each trial was equivalent to ∼80% V̇O2max (EX80%); during the final 3-min, subjects received an intervention consisting of either moderate inspiratory loading (Loadmod), heavy inspiratory loading (Loadheavy), or maximal exercise (LoadEX). Loadheavy significantly increased LM [deoxy(Hb+Mb)] from 12.2±9.0μm during EX80% to 15.3±11.7μm, and RM [deoxy(Hb+Mb)] from 5.9±3.6μm to 9.5±6.6μm. LM and RM [deoxy(Hb+Mb)] were significantly increased from EX80% to LoadEX; 12.8±9.1μm to 16.4±10.3μm and 5.9±2.9μm to 11.0±6.4μm, respectively. These data suggest an increase in respiratory muscle load increases muscle deoxy(Hb+Mb) and thus may indicate a reduction in oxygen delivery and/or increased oxygen extraction by the active muscles.

AB - The aim of this study was to determine the effect of inspiratory loading on limb locomotor (LM) and respiratory muscle (RM) deoxygenation ([deoxy (Hb+Mb)]) using NIRS during constant-power cycling exercise. Sixteen, male cyclists completed three, 6-min trials. The intensity of the first 3-min of each trial was equivalent to ∼80% V̇O2max (EX80%); during the final 3-min, subjects received an intervention consisting of either moderate inspiratory loading (Loadmod), heavy inspiratory loading (Loadheavy), or maximal exercise (LoadEX). Loadheavy significantly increased LM [deoxy(Hb+Mb)] from 12.2±9.0μm during EX80% to 15.3±11.7μm, and RM [deoxy(Hb+Mb)] from 5.9±3.6μm to 9.5±6.6μm. LM and RM [deoxy(Hb+Mb)] were significantly increased from EX80% to LoadEX; 12.8±9.1μm to 16.4±10.3μm and 5.9±2.9μm to 11.0±6.4μm, respectively. These data suggest an increase in respiratory muscle load increases muscle deoxy(Hb+Mb) and thus may indicate a reduction in oxygen delivery and/or increased oxygen extraction by the active muscles.

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KW - Near-infrared spectroscopy

KW - Resistive breathing

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Inspiratory loading and limb locomotor and respiratory muscle deoxygenation during cycling exercise

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