High-Risk Populations: The Pimas of Arizona and Mexico

Leslie O. Schulz, Lisa S. Chaudhari

Research output: Contribution to journalReview articlepeer-review

48 Scopus citations

Abstract

The purpose of this review is first, to broadly summarize the long-term commitment that began in 1965 to studying type 2 diabetes and obesity through the cooperation of the Pima Indians of Arizona, and second, to discuss the investigations with the Pima Indians of Mexico that started in 1991. The later studies emphasize gene-environment interactions in the pathogenesis of these metabolic disorders. Through the participation of both groups of Pimas, the researchers made key findings with regard to the epidemiology, physiology, clinical assessment and genetics of type 2 diabetes and obesity.

Original languageEnglish (US)
Pages (from-to)92-98
Number of pages7
JournalCurrent Obesity Reports
Volume4
Issue number1
DOIs
StatePublished - Mar 1 2015

Keywords

  • Arizona
  • Mexico
  • Pima Indians
  • Type 2 diabetes
  • environment
  • genetics
  • lifestyle
  • obesity

ASJC Scopus subject areas

  • General Medicine

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