Gold nanocluster formation using morpholino oligomer as template and assembly agent within hybrid bio-nanomaterials

Saumen Chakraborty; Reginaldo C. Rocha; Anil Desireddy; Kateryna Artyushkova; Timothy C. Sanchez; Albert T. Perry; Plamen Atanassov; Jennifer S. Martinez

doi:10.1039/c6ra16891d

Gold nanocluster formation using morpholino oligomer as template and assembly agent within hybrid bio-nanomaterials

Saumen Chakraborty
, Reginaldo C. Rocha
, Anil Desireddy
, Kateryna Artyushkova
, Timothy C. Sanchez
, Albert T. Perry
, Plamen Atanassov
, Jennifer S. Martinez

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

We report the use of a phosphorodiamidate morpholino oligomer as a DNA analogue to template the assembly of a gold nanocluster possessing 6 Au atoms and a diameter of ∼0.9 nm. Spectroscopic characterization indicates that Au preferentially binds to the phosphorodiamidate backbone as opposed to the nucleobases. A high fraction of Au(i) relative to Au(0) is observed by X-ray photoelectron spectroscopy and electrochemistry. This new nanocluster was co-assembled with carbon nanotubes and a fuel-cell enzyme, bilirubin oxidase. The hybrid bio-nanoassembly can reduce O₂ to H₂O without changing the overpotential of the enzyme.

Original language	English (US)
Pages (from-to)	90624-90630
Number of pages	7
Journal	RSC Advances
Volume	6
Issue number	93
DOIs	https://doi.org/10.1039/c6ra16891d
State	Published - 2016
Externally published	Yes

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering

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10.1039/c6ra16891d

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title = "Gold nanocluster formation using morpholino oligomer as template and assembly agent within hybrid bio-nanomaterials",

abstract = "We report the use of a phosphorodiamidate morpholino oligomer as a DNA analogue to template the assembly of a gold nanocluster possessing 6 Au atoms and a diameter of ∼0.9 nm. Spectroscopic characterization indicates that Au preferentially binds to the phosphorodiamidate backbone as opposed to the nucleobases. A high fraction of Au(i) relative to Au(0) is observed by X-ray photoelectron spectroscopy and electrochemistry. This new nanocluster was co-assembled with carbon nanotubes and a fuel-cell enzyme, bilirubin oxidase. The hybrid bio-nanoassembly can reduce O2 to H2O without changing the overpotential of the enzyme.",

author = "Saumen Chakraborty and Rocha, \{Reginaldo C.\} and Anil Desireddy and Kateryna Artyushkova and Sanchez, \{Timothy C.\} and Perry, \{Albert T.\} and Plamen Atanassov and Martinez, \{Jennifer S.\}",

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year = "2016",

doi = "10.1039/c6ra16891d",

language = "English (US)",

volume = "6",

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publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Gold nanocluster formation using morpholino oligomer as template and assembly agent within hybrid bio-nanomaterials

AU - Chakraborty, Saumen

AU - Rocha, Reginaldo C.

AU - Desireddy, Anil

AU - Artyushkova, Kateryna

AU - Sanchez, Timothy C.

AU - Perry, Albert T.

AU - Atanassov, Plamen

AU - Martinez, Jennifer S.

PY - 2016

Y1 - 2016

N2 - We report the use of a phosphorodiamidate morpholino oligomer as a DNA analogue to template the assembly of a gold nanocluster possessing 6 Au atoms and a diameter of ∼0.9 nm. Spectroscopic characterization indicates that Au preferentially binds to the phosphorodiamidate backbone as opposed to the nucleobases. A high fraction of Au(i) relative to Au(0) is observed by X-ray photoelectron spectroscopy and electrochemistry. This new nanocluster was co-assembled with carbon nanotubes and a fuel-cell enzyme, bilirubin oxidase. The hybrid bio-nanoassembly can reduce O2 to H2O without changing the overpotential of the enzyme.

AB - We report the use of a phosphorodiamidate morpholino oligomer as a DNA analogue to template the assembly of a gold nanocluster possessing 6 Au atoms and a diameter of ∼0.9 nm. Spectroscopic characterization indicates that Au preferentially binds to the phosphorodiamidate backbone as opposed to the nucleobases. A high fraction of Au(i) relative to Au(0) is observed by X-ray photoelectron spectroscopy and electrochemistry. This new nanocluster was co-assembled with carbon nanotubes and a fuel-cell enzyme, bilirubin oxidase. The hybrid bio-nanoassembly can reduce O2 to H2O without changing the overpotential of the enzyme.

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UR - https://www.scopus.com/pages/publications/84989315138#tab=citedBy

U2 - 10.1039/c6ra16891d

DO - 10.1039/c6ra16891d

M3 - Article

AN - SCOPUS:84989315138

SN - 2046-2069

VL - 6

SP - 90624

EP - 90630

JO - RSC Advances

JF - RSC Advances

IS - 93

ER -

Gold nanocluster formation using morpholino oligomer as template and assembly agent within hybrid bio-nanomaterials

Abstract

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