Gold nanocluster formation using morpholino oligomer as template and assembly agent within hybrid bio-nanomaterials

Saumen Chakraborty; Reginaldo C. Rocha; Anil Desireddy; Kateryna Artyushkova; Timothy C. Sanchez; Albert T. Perry; Plamen Atanassov; Jennifer S. Martinez

doi:10.1039/c6ra16891d

Gold nanocluster formation using morpholino oligomer as template and assembly agent within hybrid bio-nanomaterials

Saumen Chakraborty, Reginaldo C. Rocha, Anil Desireddy, Kateryna Artyushkova, Timothy C. Sanchez, Albert T. Perry, Plamen Atanassov, Jennifer S. Martinez

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

We report the use of a phosphorodiamidate morpholino oligomer as a DNA analogue to template the assembly of a gold nanocluster possessing 6 Au atoms and a diameter of ∼0.9 nm. Spectroscopic characterization indicates that Au preferentially binds to the phosphorodiamidate backbone as opposed to the nucleobases. A high fraction of Au(i) relative to Au(0) is observed by X-ray photoelectron spectroscopy and electrochemistry. This new nanocluster was co-assembled with carbon nanotubes and a fuel-cell enzyme, bilirubin oxidase. The hybrid bio-nanoassembly can reduce O₂ to H₂O without changing the overpotential of the enzyme.

Original language	English (US)
Pages (from-to)	90624-90630
Number of pages	7
Journal	RSC Advances
Volume	6
Issue number	93
DOIs	https://doi.org/10.1039/c6ra16891d
State	Published - 2016
Externally published	Yes

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering

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abstract = "We report the use of a phosphorodiamidate morpholino oligomer as a DNA analogue to template the assembly of a gold nanocluster possessing 6 Au atoms and a diameter of ∼0.9 nm. Spectroscopic characterization indicates that Au preferentially binds to the phosphorodiamidate backbone as opposed to the nucleobases. A high fraction of Au(i) relative to Au(0) is observed by X-ray photoelectron spectroscopy and electrochemistry. This new nanocluster was co-assembled with carbon nanotubes and a fuel-cell enzyme, bilirubin oxidase. The hybrid bio-nanoassembly can reduce O2 to H2O without changing the overpotential of the enzyme.",

author = "Saumen Chakraborty and Rocha, {Reginaldo C.} and Anil Desireddy and Kateryna Artyushkova and Sanchez, {Timothy C.} and Perry, {Albert T.} and Plamen Atanassov and Martinez, {Jennifer S.}",

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T1 - Gold nanocluster formation using morpholino oligomer as template and assembly agent within hybrid bio-nanomaterials

AU - Chakraborty, Saumen

AU - Rocha, Reginaldo C.

AU - Desireddy, Anil

AU - Artyushkova, Kateryna

AU - Sanchez, Timothy C.

AU - Perry, Albert T.

AU - Atanassov, Plamen

AU - Martinez, Jennifer S.

PY - 2016

Y1 - 2016

N2 - We report the use of a phosphorodiamidate morpholino oligomer as a DNA analogue to template the assembly of a gold nanocluster possessing 6 Au atoms and a diameter of ∼0.9 nm. Spectroscopic characterization indicates that Au preferentially binds to the phosphorodiamidate backbone as opposed to the nucleobases. A high fraction of Au(i) relative to Au(0) is observed by X-ray photoelectron spectroscopy and electrochemistry. This new nanocluster was co-assembled with carbon nanotubes and a fuel-cell enzyme, bilirubin oxidase. The hybrid bio-nanoassembly can reduce O2 to H2O without changing the overpotential of the enzyme.

AB - We report the use of a phosphorodiamidate morpholino oligomer as a DNA analogue to template the assembly of a gold nanocluster possessing 6 Au atoms and a diameter of ∼0.9 nm. Spectroscopic characterization indicates that Au preferentially binds to the phosphorodiamidate backbone as opposed to the nucleobases. A high fraction of Au(i) relative to Au(0) is observed by X-ray photoelectron spectroscopy and electrochemistry. This new nanocluster was co-assembled with carbon nanotubes and a fuel-cell enzyme, bilirubin oxidase. The hybrid bio-nanoassembly can reduce O2 to H2O without changing the overpotential of the enzyme.

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Gold nanocluster formation using morpholino oligomer as template and assembly agent within hybrid bio-nanomaterials

Abstract

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