Genotyping (Subtyping) Bacteria

Paul S Keim

doi:10.1016/B978-0-12-374984-0.00646-X

Genotyping (Subtyping) Bacteria

Paul S Keim

Biological Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Genotyping, or subtyping, bacteria has been practiced for decades using phenotypic variation, but recently has undergone a revolution due to DNA-based methods. Systematic sampling of nucleotide variation across whole genomes has led to the robust identification of bacterial types and subtypes. Whole genome sequencing is replacing other methods and will lead to more rigorous molecular epidemiological and evolutionary analyses.

Original language	English (US)
Title of host publication	Brenner's Encyclopedia of Genetics
Subtitle of host publication	Second Edition
Publisher	Elsevier Inc.
Pages	321-323
Number of pages	3
ISBN (Electronic)	9780080961569
ISBN (Print)	9780123749840
DOIs	https://doi.org/10.1016/B978-0-12-374984-0.00646-X
State	Published - Feb 27 2013

Keywords

Bacteria
Genotyping
MLEE
MLVA
Molecular epidemiology
PFGE
Phylogenetic trees
SNP
Subtyping
WGST

ASJC Scopus subject areas

General Agricultural and Biological Sciences
General Biochemistry, Genetics and Molecular Biology
General Medicine

Access to Document

10.1016/B978-0-12-374984-0.00646-X

Cite this

@inbook{5e49e1782e044ad0a45d7013fbb86177,

title = "Genotyping (Subtyping) Bacteria",

abstract = "Genotyping, or subtyping, bacteria has been practiced for decades using phenotypic variation, but recently has undergone a revolution due to DNA-based methods. Systematic sampling of nucleotide variation across whole genomes has led to the robust identification of bacterial types and subtypes. Whole genome sequencing is replacing other methods and will lead to more rigorous molecular epidemiological and evolutionary analyses.",

keywords = "Bacteria, Genotyping, MLEE, MLVA, Molecular epidemiology, PFGE, Phylogenetic trees, SNP, Subtyping, WGST",

author = "Keim, {Paul S}",

year = "2013",

month = feb,

day = "27",

doi = "10.1016/B978-0-12-374984-0.00646-X",

language = "English (US)",

isbn = "9780123749840",

pages = "321--323",

booktitle = "Brenner's Encyclopedia of Genetics",

publisher = "Elsevier Inc.",

}

TY - CHAP

T1 - Genotyping (Subtyping) Bacteria

AU - Keim, Paul S

PY - 2013/2/27

Y1 - 2013/2/27

N2 - Genotyping, or subtyping, bacteria has been practiced for decades using phenotypic variation, but recently has undergone a revolution due to DNA-based methods. Systematic sampling of nucleotide variation across whole genomes has led to the robust identification of bacterial types and subtypes. Whole genome sequencing is replacing other methods and will lead to more rigorous molecular epidemiological and evolutionary analyses.

AB - Genotyping, or subtyping, bacteria has been practiced for decades using phenotypic variation, but recently has undergone a revolution due to DNA-based methods. Systematic sampling of nucleotide variation across whole genomes has led to the robust identification of bacterial types and subtypes. Whole genome sequencing is replacing other methods and will lead to more rigorous molecular epidemiological and evolutionary analyses.

KW - Bacteria

KW - Genotyping

KW - MLEE

KW - MLVA

KW - Molecular epidemiology

KW - PFGE

KW - Phylogenetic trees

KW - SNP

KW - Subtyping

KW - WGST

UR - http://www.scopus.com/inward/record.url?scp=85043240849&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85043240849&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-374984-0.00646-X

DO - 10.1016/B978-0-12-374984-0.00646-X

M3 - Chapter

AN - SCOPUS:85043240849

SN - 9780123749840

SP - 321

EP - 323

BT - Brenner's Encyclopedia of Genetics

PB - Elsevier Inc.

ER -

Genotyping (Subtyping) Bacteria

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this