Frontiers in the use of biomarkers of health in research on stress and aging

Jennifer R. Piazza, David M. Almeida, Natalia O. Dmitrieva, Laura C. Klein

Research output: Contribution to journalArticlepeer-review

164 Scopus citations


Assessment of biomarkers that reflect objective indicators of physiological processes has become increasingly popular in psychological research on stress and aging. The current article reviews biomarkers of the neuroendocrine and immune systems, including issues related to measurement and normative age-related changes. We also discuss how exposure to stressors can provoke changes in these biomarkers and propose that stressful experiences may accelerate age-related declines in these systems. We recommend that future research examining physical health and aging incorporate dynamic and multivariate methods for assessing links between stressors and biomarkers.

Original languageEnglish (US)
Pages (from-to)513-525
Number of pages13
JournalJournals of Gerontology - Series B Psychological Sciences and Social Sciences
Volume65 B
Issue number5
StatePublished - Sep 2010
Externally publishedYes


  • Aging
  • Allostatic load
  • Daily diary
  • Hypothalamic-pituitary-adrenal axis
  • Immune system
  • Stress
  • Sympathetic-adrenal-medullary axis

ASJC Scopus subject areas

  • Health(social science)
  • Sociology and Political Science
  • Life-span and Life-course Studies


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