Fine-scale genetic diversity among Burkholderia pseudomallei soil isolates in northeast Thailand

Jana M. U'Ren; Heidie Hornstra; Talima Pearson; James M. Schupp; Benjamin Leadem; Shalamar Georgia; Rasana W. Sermswan; Paul Keim

doi:10.1128/AEM.00986-07

Fine-scale genetic diversity among Burkholderia pseudomallei soil isolates in northeast Thailand

Jana M. U'Ren, Heidie Hornstra, Talima Pearson, James M. Schupp, Benjamin Leadem, Shalamar Georgia, Rasana W. Sermswan, Paul Keim

Biological Sciences

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Burkholderia pseudomallei soil isolates from northeast Thailand were genotyped using multiple-locus variable-number tandem repeat (VNTR) analysis (MLVA) and multilocus sequence typing (MLST). MLVA identified 19 genotypes within three clades, while MLST revealed two genotypes. These close genetic relationships imply a recent colonization followed by localized expansion, similar to what occurs in an outbreak situation.

Original language	English (US)
Pages (from-to)	6678-6681
Number of pages	4
Journal	Applied and Environmental Microbiology
Volume	73
Issue number	20
DOIs	https://doi.org/10.1128/AEM.00986-07
State	Published - Oct 2007

ASJC Scopus subject areas

Biotechnology
Food Science
Applied Microbiology and Biotechnology
Ecology

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abstract = "Burkholderia pseudomallei soil isolates from northeast Thailand were genotyped using multiple-locus variable-number tandem repeat (VNTR) analysis (MLVA) and multilocus sequence typing (MLST). MLVA identified 19 genotypes within three clades, while MLST revealed two genotypes. These close genetic relationships imply a recent colonization followed by localized expansion, similar to what occurs in an outbreak situation.",

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AU - U'Ren, Jana M.

AU - Hornstra, Heidie

AU - Pearson, Talima

AU - Schupp, James M.

AU - Leadem, Benjamin

AU - Georgia, Shalamar

AU - Sermswan, Rasana W.

AU - Keim, Paul

PY - 2007/10

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AB - Burkholderia pseudomallei soil isolates from northeast Thailand were genotyped using multiple-locus variable-number tandem repeat (VNTR) analysis (MLVA) and multilocus sequence typing (MLST). MLVA identified 19 genotypes within three clades, while MLST revealed two genotypes. These close genetic relationships imply a recent colonization followed by localized expansion, similar to what occurs in an outbreak situation.

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Fine-scale genetic diversity among Burkholderia pseudomallei soil isolates in northeast Thailand

Abstract

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