Effects of normobaric and hypobaric hypoxia on ventilation and arterial blood gases in ducks

H. Shams; F. L. Powell; S. C. Hempleman

doi:10.1016/0034-5687(90)90080-I

Effects of normobaric and hypobaric hypoxia on ventilation and arterial blood gases in ducks

H. Shams, F. L. Powell, S. C. Hempleman

Biological Sciences

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12 Scopus citations

Abstract

We measured ventilation (V̇I) and arterial blood gases in awake Pekin ducks exposed to normoxia at sea level, normobaric hypoxia achieved by lowering FI_O₂ at normal barometric pressure (NORMO), and hypobaric hypoxia achieved with a low pressure chamber and 21% O₂ (HYPO). Average normoxic values were: V̇I = 0.46 L·(kg·min)^-1, Pa_O₂ = 99.7 Torr, Pa_CO₂ = 30.1 Torr. At PI_O₂ = 90 Torr, NORMO and HYPO measurements were not significantly different (P > 0.05). At PI_O₂ = 46 Torr, NORMO V̇I was less than HYPO V̇I but blood gases were not significantly different: V̇I = 1.00 vs 1.45 L·(kg·min)^-; Pa_O₂ = 31.3 vs 33.0 Torr; Pa_CO₂ = 11.5 vs 10.6 Torr. Although both tidal volume (VT) and respiratory frequency (fR) were greater in HYPO, similar blood gases with NORMO and HYPO suggest similar parabronchial ventilation. The results suggest increased physiologic dead space, caused by reduced efficacy of aerodynamic valving, with reduced gas density in hupobaria.

Original language	English (US)
Pages (from-to)	163-170
Number of pages	8
Journal	Respiration Physiology
Volume	80
Issue number	2-3
DOIs	https://doi.org/10.1016/0034-5687(90)90080-I
State	Published - 1990

Keywords

Aerodynamic valving
Airflow, airways of birds
Airway, airway in
Altitude, bird respiration
Animal, birds
Hypoxia, bird respiration
bird lungs

ASJC Scopus subject areas

Physiology
Pulmonary and Respiratory Medicine

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10.1016/0034-5687(90)90080-I

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title = "Effects of normobaric and hypobaric hypoxia on ventilation and arterial blood gases in ducks",

abstract = "We measured ventilation ({\.V}I) and arterial blood gases in awake Pekin ducks exposed to normoxia at sea level, normobaric hypoxia achieved by lowering FIO2 at normal barometric pressure (NORMO), and hypobaric hypoxia achieved with a low pressure chamber and 21% O2 (HYPO). Average normoxic values were: {\.V}I = 0.46 L·(kg·min)-1, PaO2 = 99.7 Torr, PaCO2 = 30.1 Torr. At PIO2 = 90 Torr, NORMO and HYPO measurements were not significantly different (P > 0.05). At PIO2 = 46 Torr, NORMO {\.V}I was less than HYPO {\.V}I but blood gases were not significantly different: {\.V}I = 1.00 vs 1.45 L·(kg·min)-; PaO2 = 31.3 vs 33.0 Torr; PaCO2 = 11.5 vs 10.6 Torr. Although both tidal volume (VT) and respiratory frequency (fR) were greater in HYPO, similar blood gases with NORMO and HYPO suggest similar parabronchial ventilation. The results suggest increased physiologic dead space, caused by reduced efficacy of aerodynamic valving, with reduced gas density in hupobaria.",

keywords = "Aerodynamic valving, Airflow, airways of birds, Airway, airway in, Altitude, bird respiration, Animal, birds, Hypoxia, bird respiration, bird lungs",

author = "H. Shams and Powell, {F. L.} and Hempleman, {S. C.}",

note = "Funding Information: Acknowledgements. We thank the University of California White Mountain Research Station and NIH/HLBI (HL 173301) for financial support and Leslie Byron, Alice Alstatt and Alan Fong for technical assistance.",

year = "1990",

doi = "10.1016/0034-5687(90)90080-I",

language = "English (US)",

volume = "80",

pages = "163--170",

journal = "Respiration Physiology",

issn = "0034-5687",

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TY - JOUR

T1 - Effects of normobaric and hypobaric hypoxia on ventilation and arterial blood gases in ducks

AU - Shams, H.

AU - Powell, F. L.

AU - Hempleman, S. C.

N1 - Funding Information: Acknowledgements. We thank the University of California White Mountain Research Station and NIH/HLBI (HL 173301) for financial support and Leslie Byron, Alice Alstatt and Alan Fong for technical assistance.

PY - 1990

Y1 - 1990

N2 - We measured ventilation (V̇I) and arterial blood gases in awake Pekin ducks exposed to normoxia at sea level, normobaric hypoxia achieved by lowering FIO2 at normal barometric pressure (NORMO), and hypobaric hypoxia achieved with a low pressure chamber and 21% O2 (HYPO). Average normoxic values were: V̇I = 0.46 L·(kg·min)-1, PaO2 = 99.7 Torr, PaCO2 = 30.1 Torr. At PIO2 = 90 Torr, NORMO and HYPO measurements were not significantly different (P > 0.05). At PIO2 = 46 Torr, NORMO V̇I was less than HYPO V̇I but blood gases were not significantly different: V̇I = 1.00 vs 1.45 L·(kg·min)-; PaO2 = 31.3 vs 33.0 Torr; PaCO2 = 11.5 vs 10.6 Torr. Although both tidal volume (VT) and respiratory frequency (fR) were greater in HYPO, similar blood gases with NORMO and HYPO suggest similar parabronchial ventilation. The results suggest increased physiologic dead space, caused by reduced efficacy of aerodynamic valving, with reduced gas density in hupobaria.

AB - We measured ventilation (V̇I) and arterial blood gases in awake Pekin ducks exposed to normoxia at sea level, normobaric hypoxia achieved by lowering FIO2 at normal barometric pressure (NORMO), and hypobaric hypoxia achieved with a low pressure chamber and 21% O2 (HYPO). Average normoxic values were: V̇I = 0.46 L·(kg·min)-1, PaO2 = 99.7 Torr, PaCO2 = 30.1 Torr. At PIO2 = 90 Torr, NORMO and HYPO measurements were not significantly different (P > 0.05). At PIO2 = 46 Torr, NORMO V̇I was less than HYPO V̇I but blood gases were not significantly different: V̇I = 1.00 vs 1.45 L·(kg·min)-; PaO2 = 31.3 vs 33.0 Torr; PaCO2 = 11.5 vs 10.6 Torr. Although both tidal volume (VT) and respiratory frequency (fR) were greater in HYPO, similar blood gases with NORMO and HYPO suggest similar parabronchial ventilation. The results suggest increased physiologic dead space, caused by reduced efficacy of aerodynamic valving, with reduced gas density in hupobaria.

KW - Aerodynamic valving

KW - Airflow, airways of birds

KW - Airway, airway in

KW - Altitude, bird respiration

KW - Animal, birds

KW - Hypoxia, bird respiration

KW - bird lungs

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DO - 10.1016/0034-5687(90)90080-I

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VL - 80

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JO - Respiration Physiology

JF - Respiration Physiology

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ER -

Effects of normobaric and hypobaric hypoxia on ventilation and arterial blood gases in ducks

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