Ebola Virus Epidemiology and Evolution in Nigeria

Onikepe A. Folarin, Deborah Ehichioya, Stephen F. Schaffner, Sarah M. Winnicki, Shirlee Wohl, Philomena Eromon, Kendra L. West, Adrianne Gladden-Young, Nicholas E. Oyejide, Christian B. Matranga, Awa Bineta Deme, Ayorinde James, Christopher Tomkins-Tinch, Kenneth Onyewurunwa, Jason T. Ladner, Gustavo Palacios, Iguosadolo Nosamiefan, Kristian G. Andersen, Sunday Omilabu, Daniel J. ParkNathan L. Yozwiak, Abdusallam Nasidi, Robert F. Garry, Oyewale Tomori, Pardis C. Sabeti, Christian T. Happi

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Containment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV genome sequences for 12 of the 20. The detailed contact data permits nearly complete reconstruction of the transmission tree for the outbreak. The EBOV genomic data are consistent with that tree. It confirms that there was a single source for the Nigerian infections, shows that the Nigerian EBOV lineage nests within a lineage previously seen in Liberia but is genetically distinct from it, and supports the conclusion that transmission from Nigeria to elsewhere did not occur.

Original languageEnglish (US)
Pages (from-to)S102-S109
JournalJournal of Infectious Diseases
StatePublished - Oct 15 2016
Externally publishedYes


  • Ebola
  • Epidemiology
  • Genomic
  • Nigeria
  • Outbreak
  • Phylogeny
  • Sequencing

ASJC Scopus subject areas

  • General Medicine


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