TY - JOUR
T1 - Daily forecasting of regional epidemics of coronavirus disease with bayesian uncertainty quantification, United States
AU - Lin, Yen Ting
AU - Neumann, Jacob
AU - Miller, Ely F.
AU - Posner, Richard G.
AU - Mallela, Abhishek
AU - Safta, Cosmin
AU - Ray, Jaideep
AU - Thakur, Gautam
AU - Chinthavali, Supriya
AU - Hlavacek, William S.
N1 - Publisher Copyright:
© 2021 Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2021/3
Y1 - 2021/3
N2 - To increase situational awareness and support evidence-based policymaking, we formulated a mathematical model for coronavirus disease transmission within a regional population. This compartmental model accounts for quarantine, self-isolation, social distancing, a nonexponentially distributed incubation period, asymptomatic persons, and mild and severe forms of symptomatic disease. We used Bayesian inference to calibrate region-specific models for consistency with daily reports of confirmed cases in the 15 most populous metropolitan statistical areas in the United States. We also quantified uncertainty in parameter estimates and forecasts. This online learning approach enables early identification of new trends despite considerable variability in case reporting.
AB - To increase situational awareness and support evidence-based policymaking, we formulated a mathematical model for coronavirus disease transmission within a regional population. This compartmental model accounts for quarantine, self-isolation, social distancing, a nonexponentially distributed incubation period, asymptomatic persons, and mild and severe forms of symptomatic disease. We used Bayesian inference to calibrate region-specific models for consistency with daily reports of confirmed cases in the 15 most populous metropolitan statistical areas in the United States. We also quantified uncertainty in parameter estimates and forecasts. This online learning approach enables early identification of new trends despite considerable variability in case reporting.
UR - http://www.scopus.com/inward/record.url?scp=85101497665&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85101497665&partnerID=8YFLogxK
U2 - 10.3201/eid2703.203364
DO - 10.3201/eid2703.203364
M3 - Article
C2 - 33622460
AN - SCOPUS:85101497665
SN - 1080-6040
VL - 27
SP - 767
EP - 778
JO - Emerging infectious diseases
JF - Emerging infectious diseases
IS - 3
ER -