TY - JOUR
T1 - Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae)
AU - Roe, Chandler C.
AU - Urbanz, Jennifer
AU - Andrews, Lela
AU - Verocai, Guilherme G.
AU - Engelthaler, David M.
AU - Hepp, Crystal M.
AU - Sahl, Jason W.
N1 - Publisher Copyright:
© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
PY - 2021
Y1 - 2021
N2 - Onchocerca lupi, Rodonaja 1967, is an emerging, zoonotic filarial nematode parasite that causes ocular disease in dogs, cats, wild canids, and humans. It is the causative agent of ocular onchocercosis in canines with increasing incidence in both North America and the Old World during the early twenty-first century. We report the complete mitochondrial genome of an O. lupi isolate from a dog from Arizona, southwestern USA, and its genetic differentiation from related Onchocerca species. The whole mitochondrial genome was obtained from whole genome sequencing of genomic DNA isolated from an adult worm. This mitogenome is 13,766 bp in size and contains 36 genes and a control region. This mitogenome provides a valuable resource for future studies involving epidemiological surveillance, population genetics, phylogeography, and comparative mitogenomics of this emerging pathogen and other parasitic nematodes.
AB - Onchocerca lupi, Rodonaja 1967, is an emerging, zoonotic filarial nematode parasite that causes ocular disease in dogs, cats, wild canids, and humans. It is the causative agent of ocular onchocercosis in canines with increasing incidence in both North America and the Old World during the early twenty-first century. We report the complete mitochondrial genome of an O. lupi isolate from a dog from Arizona, southwestern USA, and its genetic differentiation from related Onchocerca species. The whole mitochondrial genome was obtained from whole genome sequencing of genomic DNA isolated from an adult worm. This mitogenome is 13,766 bp in size and contains 36 genes and a control region. This mitogenome provides a valuable resource for future studies involving epidemiological surveillance, population genetics, phylogeography, and comparative mitogenomics of this emerging pathogen and other parasitic nematodes.
KW - Bayesian phylogenetic analyses
KW - Filaria
KW - Nematode
KW - O. lupi
KW - Onchocercosis
KW - mitogenome
UR - http://www.scopus.com/inward/record.url?scp=85111967091&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85111967091&partnerID=8YFLogxK
U2 - 10.1080/23802359.2021.1960211
DO - 10.1080/23802359.2021.1960211
M3 - Article
AN - SCOPUS:85111967091
SN - 2380-2359
VL - 6
SP - 2572
EP - 2574
JO - Mitochondrial DNA Part B: Resources
JF - Mitochondrial DNA Part B: Resources
IS - 9
ER -