TY - JOUR
T1 - Comparative Embryology of the Carotid Body
AU - Hempleman, Steven C.
AU - Warburton, Stephen J.
N1 - Funding Information:
This work was supported in part by U.S. National Institutes of Health Grant 2R15HL087269-02 to S.C. Hempleman. The authors thank the editors and anonymous reviewers for their helpful suggestions.
Publisher Copyright:
© 2012
PY - 2013/1/1
Y1 - 2013/1/1
N2 - Vertebrate carotid bodies and related structures (branchial arch oxygen chemoreceptors in fishes, carotid labyrinth in amphibians, chemoreceptors in the wall of the common carotid and its branches in birds) develop in embryos when neural crest cells, blood vessels, and nerve fibers from sympathetic and cranial nerve ganglia invade mesenchymal primordia in the wall of the 3rd branchial arch. This review focuses on literature published since the 1970's investigating similarities and differences in the embryological development of 3rd arch oxygen chemoreceptors, especially between mammals and birds, but also considering reptiles, amphibians and fishes.
AB - Vertebrate carotid bodies and related structures (branchial arch oxygen chemoreceptors in fishes, carotid labyrinth in amphibians, chemoreceptors in the wall of the common carotid and its branches in birds) develop in embryos when neural crest cells, blood vessels, and nerve fibers from sympathetic and cranial nerve ganglia invade mesenchymal primordia in the wall of the 3rd branchial arch. This review focuses on literature published since the 1970's investigating similarities and differences in the embryological development of 3rd arch oxygen chemoreceptors, especially between mammals and birds, but also considering reptiles, amphibians and fishes.
KW - branchial arch
KW - carotid body
KW - neural crest
UR - http://www.scopus.com/inward/record.url?scp=85027931381&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85027931381&partnerID=8YFLogxK
U2 - 10.1016/j.resp.2012.08.004
DO - 10.1016/j.resp.2012.08.004
M3 - Review article
C2 - 22902512
AN - SCOPUS:85027931381
SN - 1569-9048
VL - 185
SP - 3
EP - 8
JO - Respiratory Physiology and Neurobiology
JF - Respiratory Physiology and Neurobiology
IS - 1
ER -