Assessing microbiome engraftment extent following fecal microbiota transplant with q2-fmt

Chloe Herman, Evan Bolyen, Anthony Simard, Liz Gehret, J. Gregory Caporaso

Research output: Contribution to journalArticlepeer-review

Abstract

We present q2-fmt, a QIIME 2 plugin that provides diverse methods for assessing the extent of microbiome engraftment following fecal microbiota transplant. The methods implemented here were informed by a recent literature review on approaches for assessing FMT engraftment, and cover aspects of engraftment including Community Coalescence, Indicator Features, and Resilience. q2-fmt is free for all use, and detailed documentation illustrating worked examples on a real-world data set are provided in the project’s documentation.

Original languageEnglish (US)
Article numbere1013299
JournalPLoS Computational Biology
Volume21
Issue number7 July
DOIs
StatePublished - Jul 2025

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Ecology
  • Modeling and Simulation
  • Molecular Biology
  • Genetics
  • Cellular and Molecular Neuroscience
  • Computational Theory and Mathematics

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