Morphological and microchemical changes that effect to the otosclerotic stape in the Van der Hoeve's syndrome were examined with a scanning electron microscope equipped with an energy dispersive X-ray fluorescence. Using the Ca/P ratio as criterion -measured by the characteristic x-ray fluorescence- it was shown that the Van der Hoeve stape had a higher Ca/P ratio (2.6:1) as compared to the normal stape (2:1). The Van der Hoeve's syndrome lesions as poorly mineralized, with low calcium salt and apparent increase of phosphates. This finding indicates a possible change from hydroxyapatite (or apatite) to brushite, which imply an acidification of bone.
|Translated title of the contribution||Otosclerosis and Van Der Hoeven's syndrome: A contribution|
|Number of pages||9|
|Journal||Acta Otorrinolaringologica Espanola|
|State||Published - Mar 1 2001|
- Brushite and mineral composition
- Van der Hoeve syndrome
ASJC Scopus subject areas