Aportación al estudio de la otosclerosis y del síndrome de Van Der Hoeve

Translated title of the contribution: Otosclerosis and Van Der Hoeven's syndrome: A contribution

L. A. Vallejo Valdezate, J. Martín Gil, M. José-Yacamán, F. J. Martín Gil, L. M. Gil-Carcedo, J. L. Herrero Laso

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Morphological and microchemical changes that effect to the otosclerotic stape in the Van der Hoeve's syndrome were examined with a scanning electron microscope equipped with an energy dispersive X-ray fluorescence. Using the Ca/P ratio as criterion -measured by the characteristic x-ray fluorescence- it was shown that the Van der Hoeve stape had a higher Ca/P ratio (2.6:1) as compared to the normal stape (2:1). The Van der Hoeve's syndrome lesions as poorly mineralized, with low calcium salt and apparent increase of phosphates. This finding indicates a possible change from hydroxyapatite (or apatite) to brushite, which imply an acidification of bone.

Translated title of the contributionOtosclerosis and Van Der Hoeven's syndrome: A contribution
Original languageSpanish
Pages (from-to)85-93
Number of pages9
JournalActa Otorrinolaringologica Espanola
Issue number2
StatePublished - Mar 1 2001
Externally publishedYes


  • Brushite and mineral composition
  • Otosclerosis
  • Van der Hoeve syndrome

ASJC Scopus subject areas

  • Otorhinolaryngology


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