An objective approach for Burkholderia pseudomallei strain selection as challenge material for medical countermeasures efficacy testing.

Keyphrases

• Burkholderia Pseudomallei 100%
• Pseudomallei 100%
• Medical Countermeasures 100%
• Efficacy Testing 100%
• Strain Selection 100%
• Melioidosis 60%
• Biodefense 20%
• Preventive Intervention 20%
• Clinical Trials 20%
• Human Case 20%
• Genetic Characterization 20%
• Causative Agents 20%
• High Mortality 20%
• Therapeutic Intervention 20%
• High Mortality Rate 20%
• Ethical Issues 20%
• Animal Rule 20%
• Low Passage 20%
• Rule 21 20%
• Animal Infection Model 20%
• Antibiotic Treatment 20%
• Licensure 20%
• Rare Diseases 20%
• Strain-based 20%
• Human Vaccines 20%
• U.S. Food 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Burkholderia pseudomallei 100%
• Melioidosis 100%
• Infection 66%
• Clinical Trial 33%
• Disease 33%
• Antibiotics 33%
• Mortality Rate 33%
• Rare Disease 33%

Immunology and Microbiology

• Burkholderia pseudomallei 100%
• Mortality Rate 50%
• Vaccine Efficacy 50%