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Acute toxoplasmosis leads to lethal overproduction of Th1 cytokines
D. G. Mordue
, F. Monroy
, M. La Regina
, C. A. Dinarello
, L. D. Sibley
Biological Sciences
Research output
:
Contribution to journal
›
Article
›
peer-review
309
Scopus citations
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Keyphrases
Challenge Dose
66%
Chronic Toxoplasmosis
100%
Genotype
66%
Growth Rate
33%
High Dose
33%
Host Genetics
33%
Host Tissues
33%
Immune Response
33%
Infection Control
33%
Interleukin-12 (IL-12)
33%
Interleukin-18 (IL-18)
66%
Lethal Infection
100%
Liver Damage
33%
ME49
33%
Non-lethal
33%
Outbred Mice
33%
Overproduction
100%
Overstimulation
33%
RH Strain
100%
Strain Typing
66%
Th1 Cytokines
100%
Tissue Burden
33%
Toxoplasma Gondii (T. gondii)
66%
Toxoplasmosis
33%
Virulence
100%
Immunology and Microbiology
Cytokine
100%
Drug Megadose
25%
Host Tissue
25%
Immune Response
25%
Interleukin 18
50%
Low Drug Dose
75%
Mouse
25%
Neutralization
25%
Outbred Mouse Strain
25%
Toxoplasma gondii
25%
Toxoplasmosis
100%
Tumor Necrosis Factor
50%
Type Strain
50%