A spontaneous mutation in kdsD, a biosynthesis gene for 3 Deoxy-D-manno-Octulosonic Acid, occurred in a ciprofloxacin resistant strain of Francisella tularensis and caused a high level of attenuation in murine models of tularemia

Taylor Chance, Jennifer Chua, Ronald G. Toothman, Jason T. Ladner, Jonathan E. Nuss, Jo Lynne Raymond, Fabrice V. Biot, Samandra Demons, Lynda Miller, Stephanie Halasohoris, Sherry Mou, Galina Koroleva, Sean Lovett, Gustavo Palacios, Nicholas J. Vietri, Patricia L. Worsham, Christopher K. Cote, Todd M. Kijek, Joel A. Bozue

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Immunology and Microbiology

Pharmacology, Toxicology and Pharmaceutical Science