A model of the interaction between O2 and CO2 exchange and cardiopulmonary control in the duck

S. C. Hempleman; W. L. Sexton; M. R. Barker; R. E. Burger

doi:10.1016/0010-4825(79)90002-7

A model of the interaction between O₂ and CO₂ exchange and cardiopulmonary control in the duck

S. C. Hempleman, W. L. Sexton, M. R. Barker, R. E. Burger

Biological Sciences

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A simple model was used to predict resting blood gases and ventilation of ducks at sea level and at altitude. Unique features of the gas exchange model were the use of (1) empirical hyperbolic equations to predict the CO₂ content of blood and plasma, (2) plasma CO₂ content and P_CO₂ to predict the pH-dependent hemoglobin affinity for O₂ and (3) gas contents in the mass balance equations. We utilized literature data to describe ventilatory sensitivity to blood gases and the relation of arterial-venous oxygen content differences to blood flow. The model predicted values within 4% of observations.

Original language	English (US)
Pages (from-to)	167-178
Number of pages	12
Journal	Computers in Biology and Medicine
Volume	9
Issue number	3
DOIs	https://doi.org/10.1016/0010-4825(79)90002-7
State	Published - 1979

Keywords

Avian respiration
Bohr effect
Cross current exchange
Dissociation curves
Hemoglobin
Hypoxia
Parabronchus
Simulation
Ventilation-perfusion
Ventilatory sensitivity

ASJC Scopus subject areas

Computer Science Applications
Health Informatics

Access to Document

10.1016/0010-4825(79)90002-7

Cite this

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title = "A model of the interaction between O2 and CO2 exchange and cardiopulmonary control in the duck",

abstract = "A simple model was used to predict resting blood gases and ventilation of ducks at sea level and at altitude. Unique features of the gas exchange model were the use of (1) empirical hyperbolic equations to predict the CO2 content of blood and plasma, (2) plasma CO2 content and PCO2 to predict the pH-dependent hemoglobin affinity for O2 and (3) gas contents in the mass balance equations. We utilized literature data to describe ventilatory sensitivity to blood gases and the relation of arterial-venous oxygen content differences to blood flow. The model predicted values within 4% of observations.",

keywords = "Avian respiration, Bohr effect, Cross current exchange, Dissociation curves, Hemoglobin, Hypoxia, Parabronchus, Simulation, Ventilation-perfusion, Ventilatory sensitivity",

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AU - Sexton, W. L.

AU - Barker, M. R.

AU - Burger, R. E.

PY - 1979

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KW - Cross current exchange

KW - Dissociation curves

KW - Hemoglobin

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KW - Simulation

KW - Ventilation-perfusion

KW - Ventilatory sensitivity

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