TY - JOUR
T1 - A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol
AU - Espinoza-Hicks, José C.
AU - Zaragoza-Galán, Gerardo
AU - Chávez-Flores, David
AU - Ramos-Sánchez, Víctor H.
AU - Tamariz, Joaquín
AU - Camacho-Dávila, Alejandro A.
N1 - Publisher Copyright:
© Georg Thieme Verlag Stuttgart · New York. All Rights Reserved.
PY - 2018
Y1 - 2018
N2 - An efficient, general synthetic protocol for the synthesis of the biologically active benzofurans ailanthoidol, egonol and homoegonol was developed. The key starting material, eugenol, is a naturally occurring and abundant precursor. The protocol, involving sequential acylation and intramolecular Wittig reaction, provides a convenient method for building the benzofuran moiety in good yield.
AB - An efficient, general synthetic protocol for the synthesis of the biologically active benzofurans ailanthoidol, egonol and homoegonol was developed. The key starting material, eugenol, is a naturally occurring and abundant precursor. The protocol, involving sequential acylation and intramolecular Wittig reaction, provides a convenient method for building the benzofuran moiety in good yield.
KW - ailanthoidol
KW - benzofurans
KW - egonol
KW - homoegonol
KW - natural products
KW - sustainable synthesis
KW - total synthesis
UR - http://www.scopus.com/inward/record.url?scp=85052198949&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85052198949&partnerID=8YFLogxK
U2 - 10.1055/s-0037-1610169
DO - 10.1055/s-0037-1610169
M3 - Article
AN - SCOPUS:85052198949
SN - 0039-7881
VL - 50
SP - 3493
EP - 3498
JO - Synthesis (Germany)
JF - Synthesis (Germany)
IS - 17
M1 - ss-2018-m0239-op
ER -